Systems and Synthetic Biological Engineering
Chen-Yuan Kao
Education
University of Delaware, Doctoral Student, Chemical Engineering, 2013 – present
National Taiwan University, B.S., Chemical Engineering, 2008 – 2012
Research Project
Cell-derived microparticles (MPs) released from budding off the cell membrane of several type of mammalian cells. These MPs have been found playing an important role in cell-cell interaction by transffering RNA, protein and lipids. Based on the characteristics that these MP are target specific, biocompatible and immunologically inert, my project focus on engineering megakaryocyte-derived MPs as vesicles for exogenous-material-transfer, and investigating the key factors that manipulate the interactions between megakaryocyte-derived MPs with hematopoietic stem cell.
Technical Skills
- Flow Cytometry (BD FACSAriaII)
- Confocal Microscopy (Zeiss LSM880, High Speed)
Research Summary Keyword
- Cell-derived Microparticles
- Megakaryocytes